• (516) 921-3290
  • maddds@optonline.net

Trusted Dental Practice Serving Syosset and Nearby Areas


Mark A. DeNigris, DDS

“Following a tradition of dental excellence means that we make sure each and every patient receives the dentistry they need delivered in a caring, gentle manner using the latest dental technology. Our blend of old-fashioned care and leading-edge technology has earned us our patients’ trust and respect from one generation to the next.”

Following in his father’s footsteps

“This practice was established by my father, Dr. Guy DeNigris, back in 1954 and was built on developing long-term relationships with patients the old-fashioned, caring way. Like my dad, I enjoy helping people achieve healthy smiles, and my patients appreciate what I do. I can’t think of anything else that I would rather do for a living.”

  • DDS: Graduated Head of Class, Georgetown University School of Dentistry, 1980
  • BA: Catholic University, 1975
  • Licensure: State of New York

Advanced training makes the difference

“In order to continue to improve and stay current, dentists must constantly learn about new advances in care. I have always sought out the best continuing-education courses available, preferably those that allow hands-on training.”

  • Advanced Training: Includes hundreds of continuing-education hours in all aspects of dentistry

Active in professional organizations

“Professional dental organizations keep me informed of new developments in dentistry — all of which benefits you as a patient. Plus, I’ve had the opportunity to present and share techniques and difficult cases with other dentists.”

  • Member: American Dental Association, Academy of General Dentistry

In his free time, Dr. DeNigris enjoys sailboat racing, golfing, fishing and shooting.

Dominique Caucci

Office Manager

Donna LaFiandra


Lisa Russo

Dental Assistant

Our Office

If you are looking for a highly trained and experienced dentist in Syosset, you have come to the right place. At our practice, you will receive the highest quality dental care. Our dental office uses the latest state-of-the-art equipment and cutting edge technology and we uphold the strictest sterilization techniques. We know that many people may feel anxious about coming to the dentist, so it is our goal to make your visit with us as pain and anxiety free as possible. We view it as our mission to educate our patients about all of their oral health care options and to help guide them to choose a treatment plan that is most suitable and appropriate for their needs.

Scheduling Appointments

To make an appointment, simply call us or click here to Request an Appointment online.

Payment Options

We accept Mastercard, Visa, American Express and Discover credit cards as well as cash and personal checks. We accept most insurances, including those listed below. To find out more information, please call our office.

  • Aetna PPO
  • Sun Life Financial PPO
  • CIGNA Access Plan PPO
  • Delta Dental PPO
  • Dentemax PPO
  • Empire Blue Cross Blue Shield PPO
  • Guardian PPO
  • Horizon PPO
  • MetLife PPO
  • Prudential PPO
  • United Concordia PPO
  • United Healthcare PPO

Convenient Location

Our office is located at 34 South Oyster Bay Road, Syosset, NY 11791 with ample parking in our lot. Please enter your zip code or city, state below for door-to-door directions.